General Cancer Research
Imaging: Cancer Caught in the Act
Increasingly, cancer researchers are embracing the chance to spy on individual tumour cells in their native environment. Tracking cancer in live animals over time - an approach called intravital imaging.
May 7, 2014
Serious Side Effect: Several FDA-Approved Anti-Cancer Drugs Induce Stem Cell Tumors
In a surprise finding, researchers discovered that several chemotherapeutics that do stop fast growing tumors have the opposite effect on stem cells in the same animal, causing them to divide too rapidly.
March 10, 2014
New Therapies Raise Hope for a Breakthrough in Tackling Cancer
Although a range of new cancer treatments, such as targeted chemotherapy for breast cancer and cell-signaling inhibitors for leukemia, have shown positive effects over the past two decades, the checkpoint inhibitors seem to be providing uniquely long-term benefits.
February 18, 2014
Height Linked To Women's Cancer Risk? New Study Suggests Yes
Height does matter - at least it may when it comes to cancer risk.
July 25, 2013
Cancer Costs Billions Yearly in U.S. Worker Productivity: Study
The cost of lost productivity among U.S. workers with cancer is equal to 20 percent of the nation's health care spending, according to a new study.
December 17, 2012
Yale Cancer Center Finds Drug Combinations to Fight Skin Cancers More Effectively
Yale Cancer Center researchers say they've identified a series of drug combinations that may lead to better, longer-lasting treatments for a host of skin cancers.
December 13, 2012
Cancer Group Calls for FDA Crackdown on Tanning Beds
The American Cancer Society is urging federal officials to "impose greater control" over the manufacture and distribution of tanning beds, citing an elevated risk of cancer from their use.
December 13, 2012
Cancer Treatment: 'Smart Bomb' Developed
Scientists have successfully tested a capillary "smart bomb" that simultaneously attacks cancer and boosts the immune system.
July 15, 2012
Ineffectiveness of Cancer Drugs May Be due to Healthy Surrounding Cells
Researchers and doctors have consistently been baffled by cancer cases in which treatments conducted kill the cancer cells in the laboratory, but provide only partial results in patients, with the cancer returning in as little as a few months. The answers do not lie in the cancer cells themselves, but in the healthy cells in the environment next to them.
July 5, 2012
Researchers Study How Patterns, Timing of Sunlight Exposure Contribute to Skin Cancers
Researchers at Moffitt Cancer Center, the University of South Florida and the International Agency for Research on Cancer in France have studied the patterns and timing of sunlight exposure and how each is related to two nonmelanoma skin cancers - basal cell carcinoma and squamous cell carcinoma
October 23, 2012
Blood Pressure Drugs May Lengthen Lives of Melanoma Patients
Drug Shortages Roiling Oncology Practices, Impinging on Patient Care
An ongoing shortage of some crucial chemotherapy drugs is driving up the cost of the products and forcing oncologists to scramble for supplies or to find therapeutically equivalent alternatives, if there are any.
December 16, 2010
Brief Decline In Quality Of Life Seen After Brain Radiotherapy
Adjuvant whole-brain radiotherapy following surgical or radiosurgical resection of brain metastases provided no survival benefit and modestly reduced health-related quality of life when compared with close MRI observation alone in a randomized study of 359 patients.
December 15, 2010
Ultraviolet Light - Major Risk Factor In Skin Cancer
A team of researchers have reported sun's ultraviolet radiation plays a key role in proliferation and survival of skin cancer cells.
December 10, 2010
Skin Formation Study Suggests Strategies To Fight Skin Cancer
In a study published in the journal Development Cell, researchers demonstrate that a pair of enzymes called HDACs are critical to the proper formation of mammalian skin.
December 8, 2010
Cancer Risk From CT Scans May Be Lower Than Thought
Radiation-induced cancer is a big fear as the use of CT scans for all kinds of medical diagnoses increases. Clearly, unnecessary radiation should be avoided. But a new study suggests that the cancer risk may have been overestimated.
December 1, 2010
Scientists Turn a New Leaf To Discover a Compound in Daffodils That Targets Brain Cancer
A new research study published in the November 2010 print issue of The FASEB Journal offers hope that a natural compound in daffodil bulbs, called narciclasine, may be a powerful therapeutic against biologically aggressive forms of human brain cancers.
November 1, 2010
Update 2 - Delcath Cancer System Could Get OK Mid-2011--CFO
Declath Systems Inc expects to finish an application for U.S. review of its cancer drug delivery system in the fourth quarter, which would put it on track for approval by mid-2011.
September 28, 2011
Kansas Research Team Uses Particles to Battle Cancer
A team at Kansas State University is exploring the use of nano-particle induced hyperthermia to battle cancer cells in pre-clinical trials.
June 28, 2010
Shutting Out Soft Tissue Cancers in the Cold
"Cryotherapy, an interventional radiology treatment to freeze cancer tumors, may become the treatment of the future for cancer that has metastasized in soft tissues
(such as ovarian cancer) and in bone tumors."
March 16, 2010
Gene Test Aid to Cancer Treatment
To predict how well chemotherapy will work. "Starting with 829 genes in breast cancer cells, the team [Cancer Research UK] whittled down the possibilities to six genes which had an impact on whether a drug worked. They then showed that these genes could be used to predict the effectiveness of a drug called paclitaxel in patients." To try out in other cancers.
March 1, 2010
Cancer Detection Blood Test Hope
"Personalized blood tests which could track whether cancer treatment is working or if the disease has come back have been developed by US researchers."
February 19, 2010
New Stem Cell Lines Open to Research
December 2, 2009
Experimental Cancer Vaccine Goes into Clinical Trials
"Cornell University researchers have produced the first batch of a cancer vaccine known as NY-ESO-1 recombinant protein that will be used in clinical trials for patients facing either ovarian cancer or melanoma.... [I]t has been the central focus of a global network of laboratory and clinical scientists...."
September 1, 2009
SNP Link to Several Cancers [but Protect Against Melanoma]
Iceland's K. Stefansson of deCODE and others of the international team "linked common single nucleotide polymorphisms (SNPs) on chromosome 5 to five different types of cancer while at the same time conferring protection against melanoma." TERT-CLPTM1L in the chromosome 5p15 region. In Nature Genetics.
January 28, 2009
In Long-Awaited Maps of Cancer, The Breakthrough Is the Problem
3 major studies. “… [T]he picture is enormously complicated. For example, scientists had expected to identify certain key genes that were frequently mutated. They found the opposite: a large number of mutated genes, but each mutated in a smaller fraction of the tumors.”
September 5, 2008
Gene Trawl Shows Curing Cancer Harder than Thought
“The findings suggest that popular new targeted therapies may not work broadly, because they affect only one mutated gene, while cancer is caused by dozens. A better approach would be to find the pathways — networks of genes — that control a tumor's uncontrolled growth.”
September 4, 2008
Genetic Mutations Linked to Deadly Cancers. Findings of 3 Studies Focus on Brain and Pancreatic Tumors.
“The findings suggest that most solid tumors, particularly those of the brain and pancreas, won't respond to treatments that target a single gene.”
September 4, 2008
Numerous Undiscovered Gene Alterations in Pancreatic and Brain Cancers Detected
“The best hope for new therapies may lie in the discovery of agents that target the physiologic effects of the altered pathways and processes, rather than their individual genetic components."
September 4, 2008
Trouble at the Office. Comprehensive Discussion of Issues Between Drug Companies and FDA on Clinical Trials and Criteria for Cancer Drugs
Importance of “surrogate endpoints” as alternatives to overall survival data. Some history on the failure of the FDA to approve Genasense for melanoma and the new current trial.
September 12, 2008