News, Events, and Updates

News 02/19/2014

The Number of Tumor Cells Spread to Sentinel Lymph Nodes Affects Melanoma Prognosis

According to a study published in this week's PLOS Medicine by Anja Ulmer, Christoph Klein and colleagues from the Universities of Tübingen and Regensburg, Germany, the prognosis of a patient largely depends on the number of disseminated cancer cells per million lymphocytes in the sentinel node. Even very low numbers were found to be predictive for reduced survival. February 19, 2014

News 02/17/2014

A Tiny RNA With A Big Role in Melanoma

A Yale-led study has identified a key mechanism in the regulation of gene expression that promotes the proliferation of melanoma cells. The finding opens a possible avenue for development of treatments that target this mechanism. February 17, 2014

News 02/05/2014

Amgen And Merck Announce Collaboration To Evaluate Investigational Combination Treatment For Advanced Melanoma

Amgen and Merck announced today that they have entered into an agreement through a subsidiary to evaluate the safety and efficacy of talimogene laherparepvec, an investigational oncolytic immunotherapy, combined with MK-3475, an investigational anti-PD-1 immunotherapy, in a Phase 1b/2 study of patients with mid- to late-stage melanoma. February 5, 2014

News 02/04/2014

Marker May Predict Response to Ipilimumab in Advanced Melanoma

Among patients with advanced melanoma, presence of higher levels of the protein vascular endothelial growth factor (VEGF) in blood was associated with poor response to treatment with the immunotherapy ipilimumab, according to a study. February 4, 2013

News 01/06/2014

Immune Profile of Lymph Nodes Nearest to Tumor May Predict Melanoma Progression

Melanoma patients who had a specific subtype of immune cells called CD30-positive T cells in the lymph nodes closest to their tumors were more likely to have their disease progress within five years, according to data published in Cancer Research, a journal of the American Association for Cancer Research. January 6, 2014

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